Blastocyst transfer in frozen-thawed cycles.
10.5653/cerm.2012.39.3.114
- Author:
Ae Ra HAN
1
;
Chan Woo PARK
;
Hyoung Song LEE
;
Kwang Moon YANG
;
In Ok SONG
;
Mi Kyoung KOONG
Author Information
1. Department of Obstetrics and Gynecology, Kyungpook National University Hospital, Daegu, Korea.
- Publication Type:Original Article
- Keywords:
Frozen-thawed embryo transfer;
Blastocyst;
Pregnancy outcome
- MeSH:
Blastocyst;
Embryo Transfer;
Embryonic Structures;
Female;
Humans;
Pregnancy;
Pregnancy Outcome;
Pregnancy Rate;
Retrospective Studies;
Survival Rate
- From:Clinical and Experimental Reproductive Medicine
2012;39(3):114-117
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: It is well known that fresh blastocyst transfer results in better pregnancy outcomes with a smaller number of transferred embryos compared with cleavage stage embryo transfer. However, in terms of frozen-thawed blastocyst transfer, only a few studies are available. We aimed to evaluate clinical outcomes of frozen-thawed embryo transfer (FET) with blastocysts. METHODS: Retrospective analysis of FET cycles with blastocysts (B-FET) between Jan 2007 and June 2009 was performed. Age-matched FET cycles with cleavage stage embryos (C-FET) during the same period were collected as controls. A total of 58 B-FET cycles were compared with 172 C-FET cycles and also compared with those of post-thaw extended culture blastocysts from frozen pronuclear stage embryos (22 cycles). RESULTS: There was no difference in the patient characteristics of each group. The embryos' survival rates after thawing were comparable (>90%) and there was no difference in the implantation rate or clinical and ongoing pregnancy rate among the three groups. CONCLUSION: In FET, blastocyst transfers may not present better pregnancy outcomes than cleavage stage embryo transfers. A further large-scale prospective study is needed.
