The value of nuclein tumoraffin imaging,computed tomography and magnetic resonance imaging in the diagnosis of recurrent nasopharyngeal carcinoma after radiotherapy
- VernacularTitle:核素亲肿瘤显像、CT及MRI检查诊断鼻咽癌放疗后复发的价值分析
- Author:
Chefu WU
;
Bo DENG
;
Shiliang LONG
;
Xiaofeng CHEN
;
Rui LIANG
- Publication Type:Journal Article
- Keywords:
Nasopharyngeal neoplasms;
Radiotherapy;
Recurrence;
Radionuclide imaging;
Tomography,X-ray computed;
Magnetic resonance imaging
- From:
Journal of Chinese Physician
2001;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of ~(99m)Tc-MIBI tumoraffin imaging,computed tomography(CT)and magnetic resonance imaging(MRI)in the diagnosis of recurrent nasopharyngeal carcinoma(NPC) after radiotherapy.Methods The ~(99m)Tc-MIBI tumoraffin imaging,CT and MRI were performed in 78 NPC postradiotherapy patients,including 38 patients with local recurrence and 40 patients with radiofibrosis confirmed by pathology and follow-up.Results The sensitivity of ~(99m)Tc-MIBI tumoraffin imaging(73.7%) was lower than that of CT(94.7%) and MRI(92.1%).The specificity of ~(99m)Tc-MIBI tumoraffin imaging(92.5%) was obviously higher than that of CT(62.5%) and MRI(67.5%).There was no significant difference in the accuracy between three imaging examination methods.The sensitivity, specificity and accuracy of the combination of three imaging examination methods in the diagnosis of recurrent NPC after radiotherapy were 97.4%,95% and 96.2%,respectively.Conclusion The ~(99m)Tc-MIBI tumoraffin imaging has higher specificity in the diagnosis of recurrent NPC after radiotherapy.The diagnostic accuracy may be further improved with the combination of three methods.
