Correlation study of aspirin resistance and inflammatory factors in patients with coronary heart disease
- VernacularTitle:冠心病患者阿司匹林抵抗与炎症因子相关性研究
- Author:
Qin YU
;
Ning ZHU
;
Weiyi FANG
;
Jianli MAO
;
Jianguo ZONG
;
Huijun XI
;
Xiaopeng JI
;
Yan LIU
;
Hui WANG
;
Xuhua LAN
- Publication Type:Journal Article
- Keywords:
Coronary heart disease;
Aspirin resistance;
Inflammatory factors
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate correlation between aspirin resistance(AR) and inflammatory factors. Methods One hundred and ten patients with coronary heart disease took aspirin 0.1 mg/d for 14 days.It was detected platelet aggregation function induced with adenosine disphosphate (ADP) and arachidonic acid (AA), and investigated correlation between AR and inflammatory factors. Interleukin-1? (IL-1?),interleukin-6 (IL-6) and high sensitive C-reaction protein (hs-CRP) levels. Results IL-6 level of patients with AR was significantly higher than that of aspirin sensitive (AS) patients. The other two index were not different between the two groups. Conclusion IL-6 levels could be used as predictor.
