Characteristic and Analysis of Dynamic State Changes of Drug Resistance of Psedomonas Aeruginosa to Imipenem
- VernacularTitle:铜绿假单胞菌对亚胺培南耐药性的动态变化特征及分析
- Author:
Fengliang LI
;
Tingyi DU
;
Haiyun LIU
;
Rui ZHENG
;
Guangxiong ZENG
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
Imipenem;
Antibacterial;
Drug resistance
- From:
China Pharmacy
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the change in drug resistance of pseudomonas aeruginosa to imipenem bewteen Jan.2000and Jun.2005in the hospital where the authors work in order to provide the reference for rational choice of antibac-terials in clinic.METHODS:158strains of imipenem resistant pseudomonas aeruginousa had been isolated in clinic and their drug sensitivity to antibacterials was tested by KB slip diffusion method and analyzed statistically.RESULTS:Meropenem,amikacin,and ceftazidime were among the antibacterials that kept high antibacterial activity and had resistance rates less than35%included.CONCLUSIONS:Imipenem resistant pseudomonas aeruginosa strain has stronger resistance to commonly used antibacterials and its multidrug resistance is more severe.Rational use of antibacterials can help to control and lessen the drug resistance of bacteria.
