Effect of traditional Chinese medicine Jiusuyu(酒速愈) on oxygenase in liver tissue of mice with acute alcoholism
- VernacularTitle:中药酒速愈对急性酒精中毒小鼠肝脏氧化酶的影响
- Author:
Muxiang YANG
;
Zhibo WANG
;
Wentao YU
;
Huazhou XU
;
Jinkuan HU
;
Xusheng ZHANG
- Publication Type:Journal Article
- Keywords:
Jiusuyu;
acute alcoholism;
superoxide dismutase;
malondialdehyde;
catalase;
free radicals
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the effect of traditional Chinese medicine Jiusuyu(酒速愈) on activities of superoxide dismutase(SOD) and catalase(CAT),as well as the content of malondialdehyde(MDA) in liver tissues of mice with acute alcoholism.Methods: The models of acute alcoholism mice were established by drinking 56% Hongxing Erguotou(红星二锅头) drink.Eighty healthy Kunming mice were randomly divided(into) normal group,model group,high Jiusuyu dosage group,low Jiusuyiu dosage group and Gehua Jiecheng decoction(葛花解酲汤) group,with 16 animals in each group.The SOD,CAT activities and the content of MDA in(liver) tissues of each group were detected 6 hours after treatment.Results: The content of MDA in(liver) tissues of the model group was increased(P