Treatment of obstructive azoospermic patients by intracytoplasmic injection of epididymal or testicular sperm
- VernacularTitle:利用附睾或睾丸精子行卵胞浆内单精子注射治疗阻塞性无精子症
- Author:
Xiaowu FANG
;
Riran WU
;
Jianya XU
;
Yuechan LIAO
;
Jiaqi WU
- Publication Type:Journal Article
- Keywords:
Percutaneous epididymal sperm aspiration;
Testicular sperm extraction;
Intracytoplasmic injection;
Obstructive azoospermia
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To review the treatment results of intracytoplasmic injection(ICSI) of epididymal or testicular sperm obtained from 38 obstructive azoospermic patients.Methods Sperm was retrieved by percutaneous epididymal sperm aspiration(PESA) or testicular sperm extraction(TESE).Intracytoplasmic injection was performed.The rates of fertilization and clinical pregnancy were evaluated.Control group was set up in which intracytoplasmic injection was performed using sperm of ejaculation.Results Forty-one treatment cycles were performed in the 38 obstructive azoospermc patients.The rates of fertilization and clinical pregnancy were 73.3% and 53.6%.Thirty-three treatment cycles were done in the 31 ejaculatory ones.The rates of fertilization and clinical pregnancy were 75.1% and 48.4%.No significant difference was seen between the two groups.In the obstructive azoospermia group,22 clinical pregnancies were achieved including 13 live deliveries and 3 ongoing pregnancies and 6 miscarriages.In the ejaculatory group,16 clinical pregnancies were achieved including 10 live deliveries and 5 ongoing pregnancies and 1 miscarriages.Conclusions ICSI with PESA or TESE is an effective method for treatment of obstructive azoospermic patients.
