The effects of megestrolacetate on the improvement of quality of life in patients with advanced malignant neoplasms
- VernacularTitle:甲地孕酮改善晚期恶性肿瘤患者生活质量的疗效观察
- Author:
Fengqi FANG
;
Qingshan ZHU
;
Jiwei LIU
- Publication Type:Journal Article
- Keywords:
Megestrolacetate;
Advanced malignant neoplasm;
Quality of life;
Overall survival
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of megestrolacetate(MA)in improving the quality of life in patients with advanced malignant neoplasms. Methods Seventy-two patients with advanced malignant neoplasms were randomized into two groups,treatment group(37 patients) were treated with MA plus supportive care,control group(35 patients) were treated with supportive care only.The changes of appetite,weight,pain,KPS and overall survival were observed in each group.Results In the treatment group,29 cases(80.6%) got appetite improving,19 cases(52.8%) gained weight,15 cases((41.7)%)got pain relief,21 cases(58.3%)got KPS score increasing;In the control group,8 cases((22.9)%) got appetite improving,4 cases(11.4%) gained weight,3 cases(8.6%)got pain relief,5 cases(14.3%)got KPS score increasing.The differences in two groups were significant(P
