Hemodynamic response to local infiltration with different concentrations of adrenaline during endoscopic sinus surgery under general anesthesia
- VernacularTitle:利多卡因混合不同剂量肾上腺素局部浸润麻醉对全麻下鼻内窥镜手术患者血液动力学的影响
- Author:
Jianjun YANG
;
Hongjun LIU
;
Zhonghong SU
- Publication Type:Journal Article
- Keywords:
Lidocaine;
Epinephrine;
Anesthesia, local;
Anesthesia, general;
Endoscopes;
Nose;
Hemodynemic phenomena
- From:
Chinese Journal of Anesthesiology
1994;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the hemodynamic changes induced by local infiltration with different concentrations of adrenaline during endoscopic sinus surgery under general anesthesia using impedance cardiography (ICG) .Methods Sixty-nine ASA Ⅰ or Ⅱpatients of both sexes (37 males, 32 females) aged 18-60 yrs undergoing elective endoscopic sinus surgery under general anesthesia were randomized to receive local infiltration of nasal mucous membrane with 4 ml of lidocaine containing 20 ?g (group Ⅰ) or 40?g (group Ⅱ) or no adrenaline (group Ⅲ-control) . Hemodynamic changes were monitored by ICG. MAR, HR, cardiac index (CI), systemic vascular resistance index (SVRI) and acceleration index (ACI) were recorded before (baseline) and at 0.75, 1.5, 2.25, 3.0, 3.75, 4.5, 5.25 and 6.0 min after local nasal adrenaline infiltration.Results MAP was significantly decreased while HR increased at 1.5 min after adrenaline infiltration as compared to the baseline values in group Ⅰ and Ⅱ (P
