Detection of sex hormone and antisperm antibody in cryptorchidism boys after orchiopexy
- VernacularTitle:隐睾患儿术后性激素和抗精子抗体的检测
- Author:
Cuiping SONG
;
Guolin ZHANG
;
Jinlan CHEN
;
Yanfang REN
;
Kaisheng LV
;
Zhiqiang ZHAO
;
Zhan XI
- Publication Type:Journal Article
- Keywords:
Cryptorchidism;
Antisperm antibody;
Estradiol;
Testosterone;
Human chorionic gonadotropin
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(14):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research the possible influence of operation and human chorionic gonadotropin(HCG) therapy on the development of antisperm antibody (AsAb) and serum levels of estradiol (E_2) and testosterone (T) of cryptorchidism boys after orchiopexy. Methods Forty cryptorchidism boys were studied who were divided into HCG treatment group and without HCG treatment group. Twenty boys who underwent inguinal operation were studied as the operation control group and 20 normal boys as the control group. The serum were collected for detection AsAb, E_2,and T. Results There were no significant difference in serum levels of E_2 and T among the three groups(P 0.05 ). Conclusions The level of AsAb is associated with the destroy of blood barrier and the disorder of immune modulation and endocrine. Treatment with HCG has no effect on AsAb level.