Paecilomyces cicadidae total polysaccharides regulates immune function in immunosuppressed rats
- VernacularTitle:蝉拟青霉总多糖对免疫抑制大鼠组织器官免疫功能调节的实验研究
- Author:
Liqin JIN
;
Jianxin L
;
Jiezuan YANG
;
Dong LI
;
Anle LI
- Publication Type:Journal Article
- Keywords:
Paecilomyces;
Polysaccharides;
Immunosuppression;
Lipid peroxide;
Glutathione
- From:
Chinese Journal of Pathophysiology
1989;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effects of paecilomyces cicadidae total polysaccharides on the immune function and free radical scavenging of tissues in immunosuppressed rats.METHODS: The activities of lactate dehydrogenase(LDH) and arginase(Arg) in liver,kidney,spleen,thymus of immunosuppressed rats were detected by automatic biochemistry analyzer.The content of lipid peroxide(LPO) and the reduced glutathione(GSH) level in liver,kidney,spleen,thymus of immunosuppressed rats were observed.RESULTS: The activity of the LDH,Arg and GSH level were significantly increased,and the LPO content were significantly declined in liver,kidney,spleen,thymus of immunosuppressed rats induced by cyclophosphamide.CONCLUSION: Paecilomyces cicadidae total polysaccharides promote immune function and the ability of free radical scavenging of tissues in immunosuppressed rats.
