In Vitro Antibacterial Activity of Azlocillin in Combination with Tazobactam against 168 Strains of Pathogenic Bacteria
- VernacularTitle:阿洛西林与他唑巴坦联用对168株致病菌的体外抑菌活性研究
- Author:
Li DING
;
Hemin LI
;
Yanmei ZHANG
;
Aiying LIU
;
Yaping QU
- Publication Type:Journal Article
- Keywords:
Azlocillin;
Tazobactam;
The antibacterial activity in vitro;
?-lactamase inhibitor
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare the in vitro antibacterial activity of azlocillin given alone with azlocillin plus tazobactam against168strains of clinically isolated pathogenic bacteria.METHODS:The antibacterial activities of two antibac_ terials against168strains of clinically isolated pathogenic bacteria in vitro were detected by two-fold dilution method.RE-SULTS:The MIC 50 and the MIC 90 of the combined therapy of azlocillin/tazobactam(4∶1)were1/32and1/64,respectively that of azlocillin given alone.CONCLUSION:The concomitant therapy of azlocillin with tazobactam improves the antibacterial activity.