Optimization of the Extraction Technology of Oleanolic Acid from Elsholtzia Bodinieri V.by Orthogonal Test
- VernacularTitle:正交试验法优选东紫苏中齐墩果酸的提取工艺
- Author:
Haobin HU
;
Hong CAO
;
Xudong ZHENG
;
Yufeng JIAN
;
Jianxin LIU
- Publication Type:Journal Article
- Keywords:
Orthogonal test;
Microwave-assisted dynamic extraction;
Elsholtzia bodinieri V;
Oleanolic acid
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the extraction technology of oleanolic acid from Elsholtzia bodinieri V.METHODS:The extraction technology was optimized by orthogonal-test using microwave-assisted dynamic extraction method with oleanolic acid as index;And the content of oleanolic acid was determined by TLC-spectrophotometry.RESULTS:The opti-mum extraction condition was described as follows,the microwave power is600W with methanol as extracting solvent,the flow rate was8ml/min and the inner diameter of extraction tube was10mm.CONCLUSIONS:The microwave-assisted dynamic extraction method is simple,safe,rapid,accurate and with high extraction yield.The optimized extraction technology is stable and feasible,and suitable for industrialized production.