The effects of CD151 on the expression of phosphoinositide 3-kinase and the proliferation of human umbilical vein endothelial cells in vitro
- VernacularTitle:CD_(151)对脐静脉内皮细胞PI3K表达及细胞增殖的影响
- Author:
Zhenzhong ZHENG
;
Zhenxiang LIU
- Publication Type:Journal Article
- Keywords:
Antigens,CD;
Umbilical vein;
Endothelial cells;
1-phosphatidylinositol 3-kinase;
Cell proliferation
- From:
Journal of Chinese Physician
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of CD151 on the expression of phosphoinositide 3-kinase(PI3K) and the proliferation of human umbilical vein endothelial cells(HUVEC) in vitro.Methods The plasmid p-AAV-CD151 was constructed and transfected into HUVEC.The proliferation activity of HUVEC was measured by MTT colorimetric assay.The expressions of CD151 and PI3K were tested by Western Blot.Results After transfection with p-AAV-CD151,the expressions of CD151 and PI3K were significantly increased compared with those of non-transfected group and p-AAV-GFP transfected group(P
