The relationship between the expression of CD44v6,P16 protein and invasion and metastasis in gastric carcinoma
- VernacularTitle:CD44v6和P16蛋白表达与胃癌浸润和转移的关系
- Author:
Xinhua LV
;
Lang XU
;
Wensheng OU
;
Jianhui YAN
;
Kun LIAO
- Publication Type:Journal Article
- Keywords:
Stomach neoplasms;
Protein p16;
Antigens,CD44
- From:
Journal of Chinese Physician
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the expression of CD44v6,P16 protein and the invasion and metastasis in gastric carcinoma and to investigate the correlation between the expression of CD44v6 and P16 protein.Methods Immunohistochemical methods were used to detect the expression of CD44v6 and P16 protein in 110 cases of gastric carcinoma.Results In 110 cases of gastric carcinoma,the expression of CD44v6 and P16 protein were 72.7%(80/110)and 47.3%(52/110)respectively. The high level expression of CD44v6 protein and low level expression of P16 protein were positively correlated with the TNM staging,serosa infiltration,lympho node and liver metastasis of gastric carcinoma(P
