Comparative analysis on detection results of HBV preS1-Ag,HBV-DNA and HBeAg
- VernacularTitle:乙型肝炎前S1抗原与HBV-DNA和HBeAg检测结果对比分析
- Author:
Ruiqing REN
;
Shouyun CHEN
;
Binghui CHEN
- Publication Type:Journal Article
- Keywords:
Protein precursors;
Hepatitis B;
DNA,viral;
Hepatitis B e antigens;
Hepatitis B virus
- From:
International Journal of Laboratory Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical significance of HBV preS1-Ag,HBV-DNA and HBeAg in main groups of HBV infection.Methods HBV preS1-Ag and hepatitis B serum markers individually were detected by ELISA,and HBV-DNA by fluorescence quantitative PCR, then the detection results of the 308 cases were analysed.Results The serum markers of the 308 cases infected by HBV presented four modes which were "HBsAg,HBeAg,HBcAb","HBsAg,HBeAb,HBcAb","HBsAg,HBeAg","HBsAg,HBcAb".The total positive rate of preS1-Ag was 62.34%(192/308),and HBV-DNA was 78.90%(243/308).Compared HBeAg(+) groups with HBeAg(-)/anti-HBe(+) groups, the corresponding positive rates of preS1-Ag were 71.65%(139/194) and 46.49%(53/114),respectively.The difference of the two groups was significant (?~2=18.30;P
