Determination of CSF LDH and ?2-m levels for differentiating viral meningitis from purulent meningitis in pediartic patients
- VernacularTitle:脑脊液乳酸脱氢酶、?_2-微球蛋白检测对小儿化脓性脑炎与病毒性脑炎的鉴别诊断
- Author:
Tingliang ZHENG
;
Jinchi ZHANG
;
Wenjie LIN
- Publication Type:Journal Article
- Keywords:
L-lactate dehydrogenase;
?2 -microglobulin(?_2-m);
Cerebrospinal fluid;
Suppuration;
Encephalitis;
Encephalitis,viral
- From:
International Journal of Laboratory Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the significance of LDH and ?2-m concentration in CSF in differentiating viral meningitis from purulent meningitis in pediartic patients.Methods Kinetic method was performed to detect the LDH concentration in CSF in 45 patients with purulent meningitis and 49 patients with viral meningitis and 22 healthy children of control group respectively.On the other hand,radioimmunoassay(RIA)was used to detect the concentration of ?2-m.Results The concentrations of LDH in CSF in purulent meningitis group(26.15?12.17)U/L were higher than that in viral meningitis group(8.76?4.94)U/L significantly(P