Clinical analysis and pathological characteristics of lymph nodes of cat-scratch disease
- VernacularTitle:猫抓病淋巴结病理特点及临床分析
- Author:
Ming SU
;
Xupeng ZHANG
;
Chi SU
- Publication Type:Journal Article
- Keywords:
Cat-scratch disease;
Lymphadenitis;
Immunohistochemistry
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the histopathological features, immunohistochemical characteristics and clinical manifestation of lymph nodes in patients with cat-scratch disease (CSD). Methods Nineteen cases of lymph nodes of CSD were analyzed by histopathological and immunohistochemical techniques. Results All patients with CSD had a clear history of close contact with cats. The local lymph nodes were punctured swelling. The histopathological characteristics were granulomatous small abscess, lymphocytes and immunoblastic cells growing. CEA (-), EMA (-), CD_ 45 (+), CD_ 20 (+), CD_ 45 RO (+) and CD_ 68 (++) were observed in immunohistochemistry. Conclusion CSD is a self-limited infectious disease caused by cat scratching and biting, its pathogen is bartonella henselae. Its histopathological characteristics, immunohistochemical expressions and clinical history have very important meaning for the diagnosis and differential diagnosis of CSD.
