Three Cases of Generalized Granuloma Annulare in Infancy Following Bacillus Calmette-Guerin Vaccination.
- Author:
Seo Wan KIM
1
;
Tae Seok KONG
;
Tae Young HAN
;
June Hyunkyung LEE
;
Sook Ja SON
Author Information
1. Department of Dermatology, Eulji Medical Center, College of Medicine, Eulji University, Seoul, Korea. beretaya@naver.com
- Publication Type:Case Report
- Keywords:
BCG vaccine;
Granuloma annulare;
Infant
- MeSH:
Adult;
Bacillus*;
BCG Vaccine;
Connective Tissue;
Diabetes Mellitus;
Granuloma;
Granuloma Annulare*;
Humans;
Infant;
Mycobacterium bovis;
Skin Diseases;
Thyroid Diseases;
Vaccination*
- From:Korean Journal of Dermatology
2014;52(4):264-268
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Generalized granuloma annulare is a rare benign granulomatous dermatosis characterized by disseminated necrobiotic dermal papules forming an annular or nonannular configuration. It usually occurs in adults and rarely affects infants. Histologically, it presents as a lymphohistiocytic granuloma associated with varying degrees of connective tissue degeneration. Clinical associations between generalized granuloma annulare and diabetes mellitus, thyroid disease, malignancy, infection, and vaccination have been reported. There are a few cases reports of generalized granuloma annulare associated with Bacillus Calmette-Guerin (BCG) vaccination. Herein, we report three cases of generalized granuloma annulare following BCG vaccination in infants.
