Weight-reducing Drug-induced Adverse Drug Reactions:Analysis of 462 Cases
- VernacularTitle:减肥药物致462例不良反应文献分析
- Author:
Mei GUAN
;
Zhaohui JING
;
Fangfang WANG
;
Yao TANG
- Publication Type:Journal Article
- Keywords:
Weight-reducing drugs;
Adverse drug reaction;
Analysis
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the adverse drug reactions(ADRs)induced by weight-reducing drugs and to provide references for rational administration in clinics.METHODS:Classification statistic and analysis were conducted on462cases with weight-reducing drug-induced ADRs reported in62kinds of domestic and overseas medicinal periodicals published during the period of1980～2004.RESULTS:With pseudo-5-HTA appetite-suppressing drugs showing the high incidence of ADRs,which stood at36.36%of the total.Multi-systems were involved in ADRs,with the cardiovascular system showing the highest proportion(53.68%).The prognostic mortality accounted for18.61%of the total.CONCLUSION:ADRs induced by weight-reducing drugs were associated with many factors,to avoid the occurrences of which,medical workers should give more directions and monitoring on administration of drugs.
