The Clinical Effect of Aldose Reductase Inhibitor on Patients with Diabetic Neuropathy
- VernacularTitle:醛糖还原酶抑制剂对糖尿病周围神经病变的疗效观察
- Author:
Chongjuan WEI
;
Yan CHENG
- Publication Type:Journal Article
- Keywords:
Diabetic neuropathy;
Aldose reductase inhibitor;
Sensory nerve conduction velocity
- From:
Chinese Journal of Prevention and Control of Chronic Diseases
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect and safety of Epalrestat,an aldose reductase inhibitor(ARI),on patients with diabetic neuropathy.Methods 80 patients with diabetic neuropathy were randomly divided into two groups,one group were treated with Epalrestat,the other was treated with VitB12 for 16 weeks.All patients were measured on their symptoms,the physical signs and SNCV of medial nerve,ulnar nerve,peroneal nerve and tibial nerve during the treatment.Results The degrees of improvement were similar between the two groups.The subjective symptom and physical signs were significantly improved(P
