Study of combined determination of XIAP and survivin for predicting the prognosis of breast carcinoma
- VernacularTitle:XIAP和survivin联合检测判断乳腺癌预后的研究
- Author:
Xing DONG
;
Weidong ZHOU
;
Yingying JIANG
- Publication Type:Journal Article
- Keywords:
Breast Neoplasms/diag;
Adenocarcinoma/diag;
Prognosis;
XIAP;
Survivin
- From:
Chinese Journal of General Surgery
1997;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expressions of XIAP and survivin in breast carcinoma tissues and their(value) in predicting the recurrence of breast carcinoma.Methods The expression of XIAP and survivin in 65 benign and 65 malignant breast paraffin-embedded specimens was detected by using immunohistochemical assay and the results were compared.Results The positive rate of XIAP and survivin in recurrent breast carcinoma(recurrent group) was 82.2% and 85.7% respectively,and in non-recurrent breast carcinoma tissue(non-recurrent group) was 54.5% and 45.5% respectively,and in both groups were increased significantly as compared with that of benign breast tissues(20.0%,and 13.3% respectively).The positive expression of XIAP and survivin was increased significantly in recurrent group as compared with non-recurrent group(P
