Treatment of avascular necrosis of femoral head by core decompression and autograft of mesenchymal stem cells
- VernacularTitle:髓芯减压并自体干细胞移植治疗早期股骨头坏死的疗效观察
- Author:
Wuzhou WANG
;
Gengyan XING
;
Kechao ZHANG
;
Ligang MA
;
Xiaodong BAI
;
Bing LI
- Publication Type:Journal Article
- Keywords:
Femur head necrosis;
Decompression,surgical;
Stem cell transplantation
- From:
Journal of Chinese Physician
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the therapeutic effect on the treatment of avascular necrosis of femoral head by core decompression with autograft of mesenchymal stem cells(MSCs).Methods Nineteen patients with avascular necrosis of femoral head,including 8 cases of phase I,6 cases of phase II and 5 cases of phase III based on ARCO classification,were treated with core decompression with autograft of MSCs.Results The patients were followed up for one year.The average ratio of necrosis zone diminished from 31.88% to 13.18%.The Harris hip score was increased significantly.Conclusion The treatment of core decompression with autograft of MSCs is safe and effective,and it deserves to application in early necrosis of femoral head.
