Study on the relationship between children obesity and adiponectin,leptin,high-sensitive C-reactive protein
- VernacularTitle:儿童肥胖与血清脂联素、瘦素、C反-应蛋白相关性研究
- Author:
Guowen LONG
;
Xuemei HUANG
;
Yingxia DENG
;
Hui JIAN
;
Hui LONG
;
Fangqun CHEN
;
Yunwu XIAO
- Publication Type:Journal Article
- Keywords:
Obesity;
Leptin;
C-reactive protein;
Intercellular signaling peptides and proteins
- From:
Journal of Chinese Physician
2001;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between children obesity and adiponectin(ADPN),leptin(LP),and high-sensitive C-reactive protein(hsCRP).Methods Seventy-one obese volunteers as obesity group and 30 normal volunteers who matched obese volunteers in age and sex as control group were selected from 13 702 children and adolescents of 2 to 18 years old in Xiangtan city by sampling survey.The body mass index(BMI),ADPN,LP,hsCRP,fasting blood-glucose(FBG),and fasting pure insulin(INS) were checked respectively.The homeostasis model assessment for insulin resistance(HOMA-IR) and the quantitative insulin-sensitivity check index(QUICKI) were calculated.The difference between the two groups was compared and the relationship of all indexes was analyzed.Results The values of ADPN and QUICKI in obesity group were significantly lower than those of control group(P