Anti-inflammatory effects of atorvastatin on patients with acute coronary syndrome
- VernacularTitle:阿托伐他汀对急性冠脉综合征抗炎效应的临床研究
- Author:
Jun WEI
;
Yanhong WANG
- Publication Type:Journal Article
- Keywords:
Acute coronary syndrome;
C-reactive protein;
Atorvastatin
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine that atorvastatin might have anti-inflammatory effects in acute coronary syndromes(ACS) with C-reactive protein(CRP) reduction.Methods Ninety-two patients with ACS were assigned to three groups: high dose atorvastatin group(31 cases),taking atorvastatin 40 mg daily.Standard dose atorvastatin group(31 cases),taking atorvastatin 10 mg daily,and control group(30 cases),only receiving conventional therapy.CRP levels,lipid profiles were measured at first and fifth day and 1 month later.Results The study suggested:(1)CRP levels significantly decreased from baseline to the fifth day and 1 month later in high dose atorvastatin group(P
