Clinical analysis of primary hyperaldosteronism and predictive value of preoperative test for primary hyperaldosteronism
- VernacularTitle:原发性醛固酮增多症临床特点及术前诊断方法评价
- Author:
Xiaojing YU
;
Zhaohui LV
;
Xiaomei WANG
- Publication Type:Journal Article
- Keywords:
Aldosterone-producing adenoma;
Idiopathic hyperaldosteronism;
Furosemide provocation test
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical feature of the aldosterone-producing adenoma(APA) and idiopathic hyperaldosteronism(IHA)in primary hyperaldosteronism.Methods Retrospectively analyzed clinical feaures of 76 patients with APA and 17 patients with IHA.Results (1)Compared with the patients with IHA,the patients with APA had higher plasma and urinary aldosterone,lower serum potassium.(2)Furosemide provocation test(FPT)in 48 patients with APA and 14 patients with IHA were carried out.It was found that the plasma aldosterone after FPT was increased or no changed in 27 patients with adenoma,and increased in the others.It was increased in all IHA patients.(3)The diagnostic accuracy rate of CT was 84.2% in 88 patients with computed tomography imaging(CT).Conclusion The anomalies of laboratory in patients with APA are more evidence than those of IHA.The results of FPT are overlapped in a considerable amount of APA and IHA.Now those with elevation of serum aldosterone after the FPT can not exclude the adenoma.The diagnostic accuracy rate can be improved according to FPT and CT.
