The value of AFP with lectin affinity in diagnosis, differentiated diagnosis and in assessment of the effectiveness of treatment of hepatocellular carcinoma
- Author:
Vu Van Khien
- Publication Type:Journal Article
- Keywords:
hepatocellular carcinoma
- MeSH:
Carcinoma, Hepatocellular;
Therapeutics;
Diagnosis;
alpha-Fetoproteins
- From:Journal of Medical and Pharmaceutical Information
2003;0(5):27-30
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
A study was carried out on 40 hepatocellular carcinoma patients who were divided into 2 groups: 1st group (n=27) with AFP-L3<15% after treated by transcatheter oil chemoembolization (TOCE); 2nd group (n=13) with AFP-L3>15%. Results: the mean value of AFP-L3 in the 110 HCC patients was 54.623.7%, significantly higher (p<0.001) than the value in CLD (11.23.1%). When cut-off level was set 15% for AFP-L3, the sensitivity was 96.4%, and the specificity was 95%. The survival rates after 12 and 18 months of TOCE were 88.9% and 63% in the 1st group with AFP-L3<15% and 38.5% and 15.3% in the 2nd group with AFP-L3>15%, respectively. The recurrence of HCC for 1st and 2nd group were 10.23.5 months and 12.01.7 months, respectively
