Changes of serum TGF-?1 and IGF-1 in patients with essential hypertension and their related factors
- VernacularTitle:原发性高血压患者血清转化生长因子、胰岛素样生长因子含量变化及相关因素研究
- Author:
Xinyue LIU
;
Xiangqian SUI
;
Chunfeng LI
- Publication Type:Journal Article
- Keywords:
Hypertension;
Transforming growth factor beta;
Insulin-like growth factor Ⅰ;
Ventricular function,left
- From:
International Journal of Laboratory Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the association of serum transforming growth factor beta 1 (TGF-?1) and insulin-like growth factor 1 (IGF-1) with left ventricular remodeling in essential hypertension (EH) by measuring the changes of their serum levels in patients with essential hypertension (EH).Methods RIA and ELISA were used to detect serum TGF-?_1, IGF-1, AngⅡ, ALD and the left ventricular mass index (LVMI) was calculated in 59 patients with EH and in 29 normal subjects. Results The level of TGF-?1 in EH group was lower than that in normal subjects (P
