Detection and application of platelet-associated immunoglobulin
- VernacularTitle:血小板相关抗体的检测及其应用研究
- Author:
Xiaoming SUN
;
Aijun NIU
;
Yingjian CHEN
- Publication Type:Journal Article
- Keywords:
Blood platelets;
Antibodies;
Purpura,thrombocytopenic,iddopathic;
Platelet transfusion
- From:
International Journal of Laboratory Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical significance of detection of platelet-associated immunoglobulin (PAIgG).Methods Flow cytometry was used to detect PAIgG in 42 idiopathic throbocytopenic purpura (ITP) patients, 39 aplastic anemia (AA) patients, 21 patients with other autoimmune diseases and 20 normal controls. Rate of inefficient platelet infusion was calculated.Results Percentage of PAIgG positive in ITP, AA and other autoimmune diseases was higher than that in normal controls (P