Successive Assessment of Internal Quality Control for Therapeutic Drug Monitoring of Cyclosporine and Phenytoin
- VernacularTitle:环孢素和苯妥因治疗药物监测内部质控的连续性评价
- Author:
Xiaoman CHU
- Publication Type:Journal Article
- Keywords:
Therapeutic drug monitoring;
Internal quality control;
Successive assessment;
Cyclosporine;
Phenytoin
- From:
China Pharmacy
1991;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To discover early the latency factors influencing assay accuracy and to improve the quality of therapeutic drug monitoring (TDM). METHODS: The distribution and changing trend in the original data of internal quality control (IQC ) for cyclosporine and phenytoin were analyzed, and the property and source of determination errors were estimated according to the statistical theory. RESULTS: The determined data which were more or less than target values were evidently out of balance in distribution, which showed greatly significant or significant difference(P
