Bacterial Infections that with Extended Spectrum ? Lactamases(ESBLs) Production: Drug Resistance Analysis
- VernacularTitle:产超广谱?-内酰胺酶细菌感染的耐药性分析
- Author:
Lihua ZHANG
;
Qingping YU
;
Meilin YUE
- Publication Type:Journal Article
- Keywords:
Extended-spectrum ?-lactamases;
Bacteria;
Drug resistance;
Antibacterials
- From:
China Pharmacy
1991;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the incidences and drug-resistance characteristics of bacteria infections that with ESBLs production for references of clinical medication.METHODS:Escherichia coli and Klebsiella pneumoniae isolated from 2001to 2004 were subjected to ESBLs detection.The incidence of infection of each year was compared and the susceptibility test was performed by K-B paper disk method.RESULTS:Bacterial infection incidences caused by ESBLs-producing E.coli and Klebsiella pneumoniae increased year by year.Strains with ESBLs producution showed lower sensitivity to antibiotics than those without.E.coli and K.pneumoniae that with ESBLs productions showed the lowest drug resistance rates, which stood at 1.9%and 2.9%,respectively.Their drug resistances to piperacillin/tazobactam were 26.2% and 20.5%,respectively and 33.6% and 35.2%,respectively to amikacin.CONCLUSION:Carbapenem antibiotics are the optimal choice in the treatment of bacterial infections that with ESBLs production.
