Determination of 7 Kinds of Amino Acid in Compound Amino Acid Capsules with Online Derivation-Diode Array Detector
- VernacularTitle:在线衍生-二极管阵列检测器测定复方氨基酸胶囊中7种氨基酸的含量
- Author:
Nansong WANG
;
Guangming HE
;
Lijun WANG
- Publication Type:Journal Article
- Keywords:
Online derivation;
Diode array detector;
Amino acid;
Content
- From:
China Pharmacy
1991;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To develop a HPLC assay for the determination of 7 kinds of amino acids in amino acid capsules by using online derivation and diode array detector.METHODS:The high performance chromatograph of liquid with the device of automatic derivation was employed as the automatic sampler.The samples were injected in the predefined procedure,and detected with the diode array detector.RESULTS:Good resolution of 7 kinds of amino acids was obtained,and the respective detectable concentration showed a good linear relationship with its peak area.CONCLUSION:The present method is convenient,well reproduced, highly sensitive,and accurate,therefore it can be widely used.
