Compatible Stability of Gatifloxacin for Injection and Tinidazole Injection
- VernacularTitle:注射用加替沙星与替硝唑注射液的配伍稳定性考察
- Author:
Changlian WANG
;
Pinfang HUANG
;
Yiwei LIU
- Publication Type:Journal Article
- Keywords:
HPLC;
Gatifloxacin for injection;
Tinidazole injection;
Compatibility;
Stability
- From:
China Pharmacy
1991;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the compatible stability of gatifloxacin for injection with tinidazole injection.METHO_DS:Contents changes of gatifloxacin and tinidazole within 48h after mixing were determined by HPLC;and the appearance,pH value were observed and determined.RESULTS:The contents changes for both gatifloxacin and tinidazole were less than 5%. The mixed solution was clear in appearance yet without generation of gas and sediments.No significant changes were noted in pH value,color and smell.CONCLUSION:The mixed solution of gatifloxacin for injection with tinidazole injection is stable at room temperature within 48h and which can be applied in combination.
