Effects of electric stimulation at fastigial nucleus on plasma endothelin-1 and nitric oxide in patients with acute cerebral infarction
- VernacularTitle:电刺激小脑顶核对急性脑梗死患者血浆一氧化氮和内皮素-1浓度的影响及其意义
- Author:
Rufu ZHANG
;
Jin LI
- Publication Type:Journal Article
- Keywords:
electric stimulation;
fastigial nucleus;
endothelin;
nitric oxide;
acute cerebral infarction;
protective effect
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the effect of electric stimulation at fastigial nucleus (FN) on neurological deficiency score, endothelinCD*21 (ETCD*21) and nitric oxide (NO) levels and to investigate its neuroprotective effects on patients with acute cerebral infarction (ACI). Methods: Sixty-eight patients with ACI were randomly divided into two groups: the electric stimulation treatment group (electric stimulation at FN) and conventional treatment group. Forty patients with hypertension were in the control group. The neural deficiency score, concentrations of plasma ETCD*21 and NO of patients in each group were observed. Results : Compared to the conventional treatment group, the improvement of neural function, the decrease of plasma ETCD*21 and NO were more significant in the electric stimulation treatment group before and after the treatment (all P
