Evaluation of the expression of CD35 on red blood cells and CD11b on neutrophils in patients with chronic venous insufficiency
- VernacularTitle:下肢慢性静脉功能不全患者红细胞CD35和粒细胞CD11b的表达
- Author:
Lan ZHANG
;
Baigen ZHANG
;
Jiwei ZHANG
;
Hao ZHANG
- Publication Type:Journal Article
- Keywords:
Venous insufficiency;
Antibodies;
Inflammation
- From:
Chinese Journal of General Surgery
1993;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of CD35 on red blood cells (RBC) and CD11b on neutrophils in patients with chronic venous insufficiency (CVI). Methods Anticoagulated peripheral venous blood was assayed by flow cytometry for CD35 expression on RBC and CD116 on neutrophils from 42 CVI patients in different clinical picture,etiology,anatomic distribution, pathophysiology (CEAP) and clinical classes, results were compared with that of eight normal control subjects. Result Circulating neutrophils were more reactive to CDllb in CVI C5-C6 patients. Higher expression of CD35 on RBC were observed in C4 patients. Conclusion CD35 on RBC and CDllb on neutrophils may participate in the pathogenesis and to an extent reflect the severeness of CVI.
