In Vivo and in Vitro Antibacterial Action Study on Qinghou Buccal Tablets
- VernacularTitle:清喉口含片动物体内、外抑菌实验研究
- Author:
Cui CHANG
;
Chun DONG
;
Hongtu YANG
;
Dee NING
- Publication Type:Journal Article
- Keywords:
Qinghou buccal tablets;
Mouse;
Bacteriostatic action;
In vivo;
In vitro
- From:
China Pharmacy
1991;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the antibacterial actions of Qinghou buccal tablets in vivo and in vitro. METHODS: Minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of Qinghou buccal tablets were determined by standard test tube doubling dilution method;And the antibacterial action of which on staphylococcus aureus in mice in vivo were monitored. RESULTS: Qinghou buccal tablets had significant in vitro antibacterial action on staphylococcus aureus, ?-hemolytic streptococcus, ?-hemolytic streptococcus, streptococcus pneumoniae and hemophilus influenza, with MIC and MBC at 0.0 625～0.50g/ml and 0.125～1.0g/ml, respectively,and which had bacteriostatic action on mice that injected i.p. with staphylococcus aureus. CONCLUSION: Qinghou buccal tablets were proved to be of bacteriostatic actions in vitro and in vivo.
