Analysis on antibiotic prophylaxis in transurethral prostate resection of old patients with sterile urine
- VernacularTitle:经尿道前列腺电切术前无菌尿的患者行预防性抗菌的合理性评价
- Author:
Xiaoning ZHANG
;
Chunxiao LIU
- Publication Type:Journal Article
- Keywords:
Prostate;
Antibiotics;
Infection;
Transurethral prostate resection
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the efficacy of antibiotic prophylaxis in old patients with negative urine cultures,who were submitted to transurethral prostate resection(TURP).Methods One hundred and twenty old benign prostatic hyperplasia(BPH) patients with sterile urine were divided into two groups(60 patients in each group) randomly.Antibiotic group received empirical venous antibiotics 4 days postoperative.Control group received 5% glucose saline as placebo.Their postoperative infection-associated parameters were compared.Results There were no significant differences between two groups in bacteriuria and infection-associated complications at the 28th day postoperatively.The ratio of bacteriuria in antibiotic group decreased significantly at postoperative at the 4th day when compared with that of control group.The bacteriuria at postoperative at the 4th day had no specific correlation with the long-term bacteriuria,the clinical observation of bacteremia and urinal tract infection,or the culture of prostatic tissue chip.Conclusions Antibiotic prophylaxis reduces the early postoperative bacteriuria for old patients with sterile urine before TURP,but its effectiveness for postoperative infectious complications is debatable.The antibiotics according to empirical validity are not specifically sensitive to the bacteria from various sources.
