Effects of hypoxic preconditioning on the cytoskeleton of primarily cultured sinoatrial node cells of neonatal rat
- VernacularTitle:缺氧预适应对原代培养乳鼠窦房结细胞骨架结构的影响
- Author:
Qian ZHANG
;
Zhiyuan SONG
;
Shifei TONG
;
Li ZHONG
- Publication Type:Journal Article
- Keywords:
Sinoatrial node;
Hypoxic preconditioning;
Cytoskeleton
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To evaluate the effect of hypoxic preconditioning (HP) on the cytoskeleton of sinoatrial node cells primarily cultured from neonatal rat. METHODS: Cells were randomized to three groups of control, hypoxia/reoxygenation ( H/R) and HP. F-actin, vinculin, ?-tubulin and desmin were studied with laser confocal microscopy after labled with different immune fluorescent agents. RESULTS: Compared with control, although both H/R and HP reduced the fluorescence intensity of these four cytoskeletal proteins remarkably (P
