Correlation of intestinal endotoxemia, histaminemia and cellular immune function in patients with hepatitis B
- VernacularTitle:乙型肝炎患者肠源性内毒素血症、高组胺血症与细胞免疫功能之间的关系
- Author:
Hong LI
;
Dewu HAN
;
Sumei ZHANG
;
Longfeng ZHAO
- Publication Type:Journal Article
- Keywords:
Endotoxemia;
Hepatitis B;
Histamine;
Interleukins
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the correlation of intestinal endotoxemia (IETM), histaminemia and cellular immune function in the patients with hepatitis B. METHODS: Peripheral blood was collected from patients with chronic hepatitis B (n=80) and healthy individuals (n=18). According to plasma endotoxin concentration, total patients were divided into two groups: ET positive and ET negative. Serum IL-10, IL-12, IFN-?, IL-2, IL-4 concentrations were detected. In addition, the serum histamine (HA), tryptase (TS) and AP50 levels were studied. RESULTS: Compared to control group, the concentrations of IL-4 and IL-10 were increased, but IL-12 and IFN-? were decreased obviously in total patients (P
