Physiological and pathological effects of body position changes on experimental acute lung injury in rabbits
- VernacularTitle:体位改变对兔急性肺损伤生理和病理的影响
- Author:
Xinping JI
;
Zhi LIU
;
Wenying GUO
- Publication Type:Journal Article
- Keywords:
Respiratory distress syndrome, adult;
Prone position;
Supine position;
Rotate positionn;
Oleic acid;
Rabbits
- From:
Chinese Journal of Pathophysiology
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effects of body position on the physiological and pathological changes in an oleic acid-induced acute lung injury (ALI) model. METHODS: One control group and three experimental groups were set up in which the rabbits were put on supine, prone and rotation, respectively. The changes of blood pressure, heart rate and partial pressure of arterial oxygen, lung mechanics, cytokines in the course of experiment and pathologic changes were observed. RESULTS: At the end of experiment, heart rate in rotated rabbits was lower than that in prone rabbits [(176.13?26.55) beats/min vs (217.75?14.44) beats/min, P
