Study on the cell cycle of airway smooth muscle cells in asthmatic rats with airway remodeling
- VernacularTitle:哮喘气道重构时平滑肌细胞增殖周期的研究
- Author:
Weiliang GAO
;
Chen QIU
;
Jinglai QU
;
Huaqing CHEN
;
Furong LI
- Publication Type:Journal Article
- Keywords:
Asthma;
Muscle,smooth,vascular;
Cell proliferation;
Cell cycle;
Trachea
- From:
Journal of Chinese Physician
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the cell cycle of airway smooth muscle cells(ASMC) in asthmatic rats with airway remodeling and to explore a new method for the prevention and treatment of asthma.Methods The asthmatic rat models were established.The pathologic changes of inner airway wall and ASMC were determined by observing and analyzing the lung tissue sections stained with HE,and the cell cycle distribution of ASMC were analyzed by flow cytometry.Results The inner airway wall and smooth muscle layer were much thicker in rats of asthma group than those of control group(P
