The relationship between the expression of p185 、 CD44v6 and the metastasis of cervical lymphnode in laryngeal squamous cell carcinomas
- VernacularTitle:p185和CD44v6与喉癌颈淋巴结转移的关系
- Author:
Xiaoqian WANG
;
Yanchun SHAN
;
Jiqun WANG
;
Sijin LUO
- Publication Type:Journal Article
- Keywords:
Laryngeal Neoplasms;
Oncogene Proteins;
Immunohistochemistry;
Metastasis
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the rela-tionship between the expression of the proto-oncogene cerbB-2 proteins p185, level of adhesion molecules CD44v6, and lymphoid metastasis of laryngeal squa-mous cell carcinomas (LSCC). METHODS The expres-sion of p185 and CD44v6 in 63 specimen of LSCC tissues were examined by immunohistochemical method. RESULTS There was a significant difference in the expression of p185 between patient groups with and without lymphoid metastasis(P