Role of serum ?/? ratio detection in multiple myeloma diagnosis
- VernacularTitle:血清?/?轻链比值测定对多发性骨髓瘤的诊断价值
- Author:
Hua LI
;
Tan ZHAI
- Publication Type:Journal Article
- Keywords:
Multiple myeloma;
Immunoglobulins,kappa-chain;
Nephelometry and turbidimetry
- From:
International Journal of Laboratory Medicine
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of the immune rate nephelometry (IRN)in detecting the rate of serum ? and ?,and diagnosing multiple myeloma.Methods Twenty-five cases of multiple myeloma (MM),28 cases of M protein sickness and 120 cases of healthy people were detected for the rate of serum ?/? by the Immage Protein Machine the results were analyzed.Results 0.8% of healthy people was positive, the positive rate of ? and ? type M protein sickness were 23.1% and 26.7% respectively, the positive rate of ? and ? type multiple myeloma was 92.3% and 100% respectively. Conclusion The method of IRN has high sensitivity and stability in detecting the light chain of serum ? and ? on/with the Immage Protein Machine.The accuracy value of prognosing MM with the rate of serum ? and ? is better.
