Distribution of pathogens and research of drug resistance on 712 sputum specimens
- VernacularTitle:712例痰标本病原菌分布及耐药性调查
- Author:
Dongmei YOU
- Publication Type:Journal Article
- Keywords:
Sputum;
Pathogens;
Drug tolerance
- From:
International Journal of Laboratory Medicine
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution and the drug resistance of pathogens isolated from 712 sputum specimens in the hospital.Methods 712 sputum specimens collected from the hospital underwent microorganism culture and drug sensitivity test.Disc diffusion screening and the K-B disc diffusion confirmatory method were applied to detect ESBLs,K-B test was used to judge their sensitivityies to drugs.Results The positive rate of sputum culture was increasing apparently(38% in 2003,49% in 2004 respectively).Pseudomonas aeruginosa,Escherichia coli,Klebsiella pneumoniae,and Staphylococcus epidermidis,Enterobacter,and Staphylococcus aureus were six most commonly detected oxygen-dependent bacterias.The results of the drug resistance test showed that the multiple drug resistance to antibiotics was serious.More and more enterobacteriaceae producing ESBLs were found.Conclusion Gram-negative bacilli are the major pathogens in the sputum culture,multiple drug resistance is serious. Therefore monitoring drug resistance is very important for instructing clinical doctors to use antibiotics properly.
