Preparation and Quality Control of Oceanic Lysozyme Film
- VernacularTitle:海洋溶菌酶膜的制备及质量控制
- Author:
Wei SUN
;
Xiufen QI
;
Enze LI
;
Yuai LIU
;
Liling DAI
- Publication Type:Journal Article
- Keywords:
Oceanic lysozyme film;
Concentration of albumen;
Enzyme activity;
Contents;
Stability
- From:
China Pharmacy
1991;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare oceanic lysozyme film and establish a method for its quality control.METHODS:Film agent was prepared with oceanic lysozyme as the principle agent and hydroxy propyl methylcellulose as the film-former.Folin-phenol method and agar plate diffusion method were used respectively to determine the concentration of albumen and enzyme activity of oceanic lysozyme;and the content of lysozyme in the oceanic lysozyme film was determined by ultraviolet spectrophotometry.RESULTS:Both albumen concentration and enzyme activity of oceanic lysozyme were up to the bacte?riostatic requirement.The average recovery rate of sample was101.0%(RSD=0.67%).Storing within6months,each index of the sample experienced no marked change.CONCLUSION:The preparation is simple in production,controllable in quality and it served as a new preparation for the clinical treatment of vaginitis.