Haplogroup diversity of 8 biallelic markers on human Y chromosome in Wuhan Han population
- VernacularTitle:武汉汉族8个Y染色体双等位基因标记遗传多态性
- Author:
Daixin HUANG
- Publication Type:Journal Article
- Keywords:
Forensic biological evidence;
Y chromosome;
Biallelic marker;
Tragment length discrepant allele specific PCR;
Haplogroup
- From:
Chinese Journal of Forensic Medicine
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To screen polymorphic biallelic markers on human Y chromosome in Han population , calculations of their allele and haplogroup frequency distributions to provide data for forensic application and population evolution studies. Methods Genotyping of 8 biallelic markers on human Y chromosome (M9, M89, M111, Ml19, M122, M134, IMS-JST0033050 and SRY +465) were carried out in a sample of 160 unrelated Chinese male individuals living in Wuhan using fragment length discrepant allele specific PCR (FLDAS-PCR) and PAGE technique. Results Genetic polymorphism were identified for all 8 biallelic markers in Wuhan Han population. Gene Diversity (GD) ranges from 0.0126 to 0.4830. A total of 9 different haplogroups(Hg 1-9)were observed and the haplogroup diversity (HD) were 0.7776. Conclusion The haplogroups formed by 8 biallelic markers are highly polymorphic, and can be used in conjunction with Y-STRs in forensic medicine and population evolution studies.
