Study on blood drug level of 8 Lidocaine anaphylactic deaths
- VernacularTitle:8例利多卡因过敏性休克死的血药浓度分析
- Author:
Yingqiang LU
;
Zhaoyan XUAN
;
Baijun CUI
- Publication Type:Journal Article
- Keywords:
Forensic toxicology;
Lidocaine;
Anaphylactic shock;
Blood drug level;
High performance liquid chromatography(HPLC)
- From:
Chinese Journal of Forensic Medicine
1986;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between Lidocaine blood drug level and the cause of death from Lidocaine anaphylactic shock. Method Comparing and analyzing the blood drug levels by HPLC between two groups of people whose various indexes are normal before the surgery. Group 1 included 8 cases who accepted Lidocaine as anesthetic and died from Lidocaine anaphylactic shock. Group 2 included 11 cases who also took Lidocaine as anesthetic and passed the surgery smoothly. Results Lidocaine blood level of Group 1 (1.61?0. 45mg/L) is lower than that of Group 2 (2. 44 ?0. 47mg/L). Conclusion Lidocaine blood drug level has nothing to do with the cause of Lidocaine anaphylactic shock.
