Treating Acute Bacterial Infections with Oral Gatifloxacin and Levofloxacin:Evaluation on Pharmacoeconomic
- VernacularTitle:加替沙星与左氧氟沙星口服治疗急性细菌性感染的药物经济学评价
- Author:
Yuhe WANG
- Publication Type:Journal Article
- Keywords:
Acute Bacterial infection;
Gatifloxacin;
Levofloxacin;
Cost-minimization analysis;
Cost-effectiveness analysis
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the cost-effectiveness of oral gatifloxacin and levofloxacin in the treatment of acute bacterial infections.METHODS:224cases with acute bacterial infections treated with oral gatifloxacin(group A)and levofloxacin(group B)were collected respectively by reviewing literature,the analysis and evaluation was performed by cost-minimization analysis and cost-effectiveness analysis in pharmacoeconomics.RESULTS:Total effective rates of group A and B were95.6%and91.8%,respectively;Minimum costs for each case were(287.1?95.7)and(109.5?36.5)yuan,respectively;Calculated from the perspective of total effective rates,the cost-effectiveness ratios were(14.67?2.13)and(13.58?1.65),respectively;The incremental cost-effectiveness ratio of group A as against group B was41.CONCLUSION:Levofloxacin is of better cost-effectiveness advantage than gatifloxacin in the treatment of acute bacterial infections.