Content Determination of Costunolide in Liqifuwei Oral Liquid by RP-HPLC
- VernacularTitle:反相高效液相色谱法测定理气复胃口服液中木香烃内酯的含量
- Author:
Rongsheng TONG
;
Shiming SUN
;
Zhengzhong WU
- Publication Type:Journal Article
- Keywords:
RP-HPLC;
Liqifuwei oral liquid;
Costunolide;
Content determination
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a RP-HPLC method for content determination of costunolide in Liqifuwei oral liquid.METHODS:The assay was performed on a Luna C 18 column by UV detector at the wavelength of225nm with methanol-water(72∶28)as the mobile phase at the flow rate of1.0ml/min.RESULTS:The amount of costunolide was linear with its area over the range from0.2?g～2.0?g(r=0.9996),the average recovery was98.4%(RSD=0.85%).CONCLUSION:The present method is convenient,sensitive and accurate with good reproducibility and can be used for the quality control of Liqifuwei oral liquid.
