Toxicity and anti-bacterial effect of CTK vaginal tablet against some bacteria causing inferior genital tract inflammation
- Author:
Le Thi Oanh
- Publication Type:Journal Article
- Keywords:
Inferior genital tract inflammation
- MeSH:
Inflammation;
Genital Diseases, Female;
Vaginal Creams, Foams, and Jellies;
drugs
- From:Journal of Practical Medicine
2003;442(2):14-16
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Inflammation; Genital Diseases, Female ;Vaginal Creams, Foams, and Jellies; drugs;
CTK vaginal tablet’s antibacterial effect was evaluated in vitro through the determination of minimal inhibition effect of this tablet in various strains of E.coli and S.aureus subchronical toxicity and effect of this medicament on the tissue were investigated. Results showed that CTK in 1/150 solution is capable to inhibite completely the growth of S.aureus, and in 1/100 solution to E.coli. In applying into rabbit vagina CTK made vaginal pH decreased. CTK dose of 0.05-0.06 g/kg did not influence on blood white cell counts, red cell counts, platelet counts and Hb level in rabbit. CTK did not influence on SGOT, SGPT enzyme activity, improving the content of albumin and of cholesterol of the rabbit
