Expression and clinical biological significance of fibroblast specific protein-1 in human lung cancer tissue
- VernacularTitle:成纤维细胞特异蛋白-1在肺癌中的表达及其临床生物学意义
- Author:
Zhongmin SUN
;
Xiangli CHEN
;
Hongyan WANG
;
Xiaoyan CHEN
;
Min WANG
;
Guanjun ZHANG
- Publication Type:Journal Article
- Keywords:
Lung cancer;
Fibroblast specific protein-1;
Infiltration and metastasis
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the expression of fibroblast specific protein-1 (S100A4) in human lung cancer,and investigate roles of S100A4 in the infiltration and metastasis of lung cancer. Methods Immunohistochemical S-P method was used to detect the expression of S100A4 in 50 lung cancer tissues and 6 normal lung tissues. Results The expression of S100A4 was up-regulated in lung cancer tissues.Significant differences of the expression rates of S100A4 was found between lung cancer and normal groups (P
